Puberty and pubertal growth dynamics in children with idiopathic short stature.
J Pediatr Endocrinol Metab
; 24(5-6): 319-25, 2011.
Article
en En
| MEDLINE
| ID: mdl-21823530
ABSTRACT
OBJECTIVE:
As the prognosis for final height is unfavorable for children with idiopathic short stature (ISS), we studied the pubertal growth dynamics in these children, which is a determinant factor in final height. SUBJECTS/METHODS:
In a retrospective cohort study, we analyzed the pubertal period, age of puberty and peripubertal growth in 50 children with ISS.RESULTS:
The onset of puberty occurred later. Growth rate tended to become increasingly subnormal in the prepubertal period and height was -2.45 SD at puberty onset. Growth reaccelerated at this point, which tended to correct the deviation from the mean height, but it was insufficient to obtain a normal final height.CONCLUSIONS:
The dynamics of growth in children with ISS showed a distinct pattern in the prepubertal and pubertal periods and puberty is significantly delayed in this population. These patterns could explain the unfavorable prognosis for children with ISS.
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Banco de datos:
MEDLINE
Asunto principal:
Estatura
/
Pubertad
/
Trastornos del Crecimiento
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Año:
2011
Tipo del documento:
Article