[Klinefelter syndrome: spermatogenesis and quality of gametes]. / Syndrome de Klinefelter : qualité des gamètes et spermatogenèse.
Gynecol Obstet Fertil
; 39(9): 525-8, 2011 Sep.
Article
en Fr
| MEDLINE
| ID: mdl-21835669
ABSTRACT
Klinefelter syndrome is defined by the presence of a supernumerary X chromosome in a phenotypic male. It is the most frequent gonosomic anomaly in infertile men with an incidence of 0.1 to 0.2% in newborn males. The presence of an additional X chromosome induces spermatogenic failure but when gametes are present, they are usually normal. The risk of transmission of the chromosomal anomaly remains low. In the literature, only one 47,XXY foetus resulting from more than a hundred births from fathers with Klinefelter syndrome, has been reported. One can estimate, that a TESE performed in half of the patients with non-mosaic 47,XXY will be positive and may enable IVF/ICSI to be achieved.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Espermatogénesis
/
Espermatozoides
/
Síndrome de Klinefelter
Límite:
Humans
/
Male
Idioma:
Fr
Año:
2011
Tipo del documento:
Article