Immunohistochemical detection of parvovirus B19 in "gloves and socks" papular purpuric syndrome: direct evidence for viral endothelial involvement. Report of three cases and review of the literature.
Am J Dermatopathol
; 33(8): 790-5, 2011 Dec.
Article
en En
| MEDLINE
| ID: mdl-22024574
ABSTRACT
Papular-purpuric "gloves and socks" syndrome is a distinctive dermatosis featuring acral pruritus, edema, and petechiae. It has been attributed in most--but not all--reported cases to Parvovirus B19 infection, on the grounds of serological proof of recent infection or detection of viral DNA by polymerase chain reaction in patient serum or biopsies. We report the immunohistochemical detection of Parvovirus B19 VP2 structural protein in the endothelial lining of dermal blood vessels in 3 examples of Papular-purpuric "gloves and socks" syndrome and review previously described immunohistochemical investigations in cutaneous involvement by this infection.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Inmunohistoquímica
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Parvovirus B19 Humano
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Infecciones por Parvoviridae
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Proteínas de la Cápside
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Dermatosis del Pie
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Dermatosis de la Mano
Tipo de estudio:
Diagnostic_studies
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Prognostic_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2011
Tipo del documento:
Article