Aloysia triphylla infusion protects rats against dextran sulfate sodium-induced colonic damage.
J Sci Food Agric
; 92(7): 1570-2, 2012 May.
Article
en En
| MEDLINE
| ID: mdl-22190244
ABSTRACT
BACKGROUND:
Inflammatory bowel diseases consist of uncontrolled intestinal inflammation leading to mucosal disruption. Polyphenols are micronutrients with antioxidant and anti-inflammatory properties and may play an interesting role in the prevention of intestinal inflammation. Lemon verbena (Aloysia triphylla (L'Herit.) Britton, Verbenaceae) infusion is a popular herbal drink rich in polyphenols. This study evaluated the protective effects of lemon verbena infusion consumption on the development of dextran sulfate sodium (DSS)-induced colitis in rats. The infusion was given to rats as a drink providing 82 µmol polyphenols day(-1) for 21 days. Colitis was induced with 40 g l(-1) DSS in the drink for the last 7 days.RESULTS:
Lemon verbena infusion treatment restored body weight gain and prevented colonic shortening. Despite no protective effect on myeloperoxidase activity, A. triphylla infusion limited histological colonic alterations.CONCLUSION:
The results suggest that lemon verbena infusion partially protects rats against DSS-induced inflammation.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Aumento de Peso
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Colitis
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Colon
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Verbenaceae
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Polifenoles
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Fitoterapia
Límite:
Animals
Idioma:
En
Año:
2012
Tipo del documento:
Article