Volumetric MRI and MRS and early motor development of infants born preterm.
Pediatr Phys Ther
; 24(1): 38-44, 2012.
Article
en En
| MEDLINE
| ID: mdl-22207464
ABSTRACT
PURPOSE:
To investigate the relationship between volumetric magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) in infants born less than 30 weeks gestation and early motor development at 6 months adjusted age.METHODS:
Twenty infants born preterm and 4 born at term (control) underwent MRI with volumetric analysis and MRS prior to neonatal intensive care unit discharge. Infants were assessed using the Bayley Scale of Infant Development at 6 months adjusted age.RESULTS:
At 6 months, infants born preterm with low motor scores had a reduction in their subcortical gray matter. No differences were detected in other brain structures. N-acetylaspartate/choline correlated with white matter (R = 0.45, P = .03), gray matter (R = 0.43, P = .04), and cerebellar volume (R = 0.6, P = .002) but not with 6-month motor performance.CONCLUSION:
There is an association between diminished subcortical gray matter volume and low motor scores. Our data suggest that volumetric MRI performed prior to hospital discharge may have some role in counseling parents about potential motor delays.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Encéfalo
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Recien Nacido Prematuro
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Imagen por Resonancia Magnética
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Espectroscopía de Resonancia Magnética
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Destreza Motora
Tipo de estudio:
Etiology_studies
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Observational_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Año:
2012
Tipo del documento:
Article