Preliminary crystal structure analysis of an Fab specific for a Salmonella O-polysaccharide antigen.
J Mol Biol
; 215(4): 489-92, 1990 Oct 20.
Article
en En
| MEDLINE
| ID: mdl-2231716
ABSTRACT
The Fab from an IgG1, lambda murine monoclonal antibody with specificity for the O-polysaccharide antigen of Salmonella typhimurium has been crystallized in the absence and presence of hapten. The conditions for crystal growth were vapor diffusion equilibration with 16 to 23% polyethylene glycol 8000 solutions. Data have been collected from crystals of the complex in space group P212121, a = 60.6 A, b = 111.3 A, c = 61.1 A, and refinement of a molecular replacement solution is underway.
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Banco de datos:
MEDLINE
Asunto principal:
Azúcares de Poliisoprenil Fosfato
/
Salmonella typhimurium
/
Fragmentos Fab de Inmunoglobulinas
/
Antígenos O
/
Antígenos Bacterianos
Límite:
Animals
Idioma:
En
Año:
1990
Tipo del documento:
Article