Schizophrenia genetics: progress, at last.
Curr Opin Genet Dev
; 22(3): 238-44, 2012 Jun.
Article
en En
| MEDLINE
| ID: mdl-22424801
ABSTRACT
The heritability of schizophrenia is well established, and has motivated the search for genetic variation that contributes to susceptibility. Recent progress from both genome-wide association and copy number variant studies have identified risk loci, however, these are at very different ends of the susceptibility spectrum with respect to allele frequency and effect size. It is likely that investigations of common variants have surrendered their full yield, but rare variant exploration is at the very beginning.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esquizofrenia
/
Predisposición Genética a la Enfermedad
/
Variaciones en el Número de Copia de ADN
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Año:
2012
Tipo del documento:
Article