Pathogenesis of nephrolithiasis: recent insight from cell biology and renal pathology.
Clin Cases Miner Bone Metab
; 5(2): 107-9, 2008 May.
Article
en En
| MEDLINE
| ID: mdl-22460990
ABSTRACT
Randall's plaques are very common in idiopathic calcium-oxalate nephrolithiasis. These papillary plaques have an apatite mineral structure. While these calcium deposits are generally assumed to be secondary to a purely physico-chemical phenomenon, we advance the hypothesis that they form due to a truly ectopic biomineralization in the renal tissue, and that Henle's loop epithelial cells, or pericyte-like interstitial cells, or papillary stem cells differentiating along a bone lineage might be involved.
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Banco de datos:
MEDLINE
Tipo de estudio:
Etiology_studies
Idioma:
En
Año:
2008
Tipo del documento:
Article