Can the battle against tuberculosis gain from epigenetic research?
Trends Microbiol
; 20(5): 220-6, 2012 May.
Article
en En
| MEDLINE
| ID: mdl-22464289
ABSTRACT
A healthy immune system needs to be highly plastic to cope with host defense and surveillance. What mechanisms provide this plasticity? Considering the threat of infectious diseases to a large part of the world's population, can these mechanisms possibly be of use in the ongoing battle against infectious diseases? Against the backdrop of the pandemic nature of tuberculosis, we discuss whether and how epigenetic mechanisms can shed light on our understanding of infectious disease, and if epigenetic marks can be employed to monitor latent infection, disease reactivation or treatment response.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis
/
Epigenómica
Límite:
Animals
/
Humans
Idioma:
En
Año:
2012
Tipo del documento:
Article