Tumour necrosis factor &#945; secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice.

Sendler, Matthias; Dummer, Annegret; Weiss, Frank U; Krüger, Burkhard; Wartmann, Thomas; Scharffetter-Kochanek, Karin; van Rooijen, Nico; Malla, Sudarshan Ravi; Aghdassi, Ali; Halangk, Walter; Lerch, Markus M; Mayerle, Julia

Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice.

Sendler, Matthias; Dummer, Annegret; Weiss, Frank U; Krüger, Burkhard; Wartmann, Thomas; Scharffetter-Kochanek, Karin; van Rooijen, Nico; Malla, Sudarshan Ravi; Aghdassi, Ali; Halangk, Walter; Lerch, Markus M; Mayerle, Julia.

Sendler M; Department of Medicine A, University Medicine, Ernst-Moritz-Arndt-University, Greifswald, Friedrich-Loeffler-Str. 23a, 17475 Greifswald, Germany.

Gut ; 62(3): 430-9, 2013 Mar.

Article en En | MEDLINE | ID: mdl-22490516

Asunto(s)

Células Acinares/patología; Caspasa 3/metabolismo; Catepsina B/metabolismo; Pancreatitis Aguda Necrotizante/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Animales; Western Blotting; Antígenos CD18/inmunología; Movimiento Celular; Ceruletida/efectos adversos; Activación Enzimática; Leucocitos/fisiología; Ratones; Necrosis/patología; Pancreatitis Aguda Necrotizante/inducido químicamente; Pancreatitis Aguda Necrotizante/enzimología; Pancreatitis Aguda Necrotizante/patología; Péptido Hidrolasas/metabolismo; Factor de Necrosis Tumoral alfa/antagonistas & inhibidores

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Catepsina B / Factor de Necrosis Tumoral alfa / Pancreatitis Aguda Necrotizante / Caspasa 3 / Células Acinares Límite: Animals Idioma: En Año: 2013 Tipo del documento: Article

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