[Rubella seroprevalence in Tunisian childbearing women two years after vaccination program introduction]. / Séroprévalence de la rubéole chez la femme en âge de procréer deux ans après l'introduction de la vaccination en Tunisie.
Pathol Biol (Paris)
; 60(3): 170-3, 2012 Jun.
Article
en Fr
| MEDLINE
| ID: mdl-22578467
ABSTRACT
UNLABELLED Acquiring rubella during the first 20 weeks of pregnancy can lead to teratogenic effects. AIM:
The aim of the study was to investigate the impact of rubella vaccination strategy two years after its introduction in Tunisia in 2005.METHODS:
This study was conducted over two periods, 2000 and 2007-2008. A total of 15,776 childbearing women were enrolled in the sample. Serological studies were performed by using the ELISA method.RESULTS:
Overall, rubella infection seroprevalence did not increase between 2000 and 2007-2008. Nevertheless, a significant increase in seroprevalence, from 78.2% in 2000 to 92% in 2007-2008 (P=0.006), was especially noted in the age group under 20 years. Seroprevalence did also statistically increase with parity in 2007-2008 from 77.4% in women without any parity to 89.8% in women with over three parities (P=0.01).CONCLUSIONS:
Results improvements seem most likely due to mass vaccination campaign for girls aged from 13 to 18 years in 2005, and also routinely post-partum vaccination of seronegative pregnant women or women ignoring their rubella status. In the coming years, systematic selective immunization of 12-year-old schoolgirls who are not yet entering their prime childbearing years will achieve female population sufficient immunity.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones Infecciosas del Embarazo
/
Rubéola (Sarampión Alemán)
/
Vacuna contra la Rubéola
/
Vacunación Masiva
/
Anticuerpos Antivirales
Tipo de estudio:
Evaluation_studies
/
Sysrev_observational_studies
Límite:
Adolescent
/
Adult
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Female
/
Humans
/
Pregnancy
País como asunto:
Africa
Idioma:
Fr
Año:
2012
Tipo del documento:
Article