Hypoglycemic effects of hyaluronate-endo-ß-N-acetylhexosaminidase immobilized by electron beam synthesis nanotechnology.
Bull Exp Biol Med
; 153(1): 94-7, 2012 May.
Article
en En
| MEDLINE
| ID: mdl-22808503
ABSTRACT
Hypoglycemic effect of hyaluronate-endo-ß-N-acetylhexosaminidase immobilized by electron-beam synthesis nanotechnology (imHEA-HA) was studied in experimental insulin-dependent and insulin-independent diabetes mellitus. The drug exhibited a hypoglycemic effect of its own and potentiated the pharmacological effect of exogenous insulin injected in vivo. Studies on liver cell culture demonstrated an increase of cell sensitivity to insulin after treatment with imHEA-HA.
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Banco de datos:
MEDLINE
Asunto principal:
Beta-N-Acetilhexosaminidasas
/
Nanotecnología
/
Enzimas Inmovilizadas
/
Glicosaminoglicanos
/
Hipoglucemiantes
Límite:
Animals
Idioma:
En
Año:
2012
Tipo del documento:
Article