[Hemophagocytic syndrome secondary to cavitary pulmonary tuberculosis]. / Syndrome d'activation macrophagique secondaire à une tuberculose pulmonaire cavitaire.
Med Sante Trop
; 22(1): 99-101, 2012.
Article
en Fr
| MEDLINE
| ID: mdl-22868740
ABSTRACT
Hemophagocytic syndrome is due to the activation and nonmalignant proliferation of macrophages and T lymphocytes. The purpose of this report is to describe a 25-year-old man who presented with fever, coughing, and weight loss over the past month. Laboratory findings demonstrated pancytopenia, hyperferritinemia, and cytolysis. The myelogram showed a hemophagocytic syndrome, and tuberculosis bacilli were found in the sputum. Chest radiography and thoracic computed tomography depicted a cavitary lesion suggestive of pulmonary tuberculosis. Treatment of tuberculosis alone, without an immunosuppressant agent, was effective and led to improvement. In a country where tuberculosis is highly endemic, hemophagocytic syndrome should be considered in the differential diagnosis of patients with active tuberculosis complicated by pancytopenia.
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Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis Pulmonar
/
Linfohistiocitosis Hemofagocítica
Límite:
Adult
/
Humans
/
Male
Idioma:
Fr
Año:
2012
Tipo del documento:
Article