Apoptosis as a mechanism of maxillary sinus mucosa injury in rats after experimental transection of the maxillary nerve.

Edranov, S S; Motavkin, P A

Edranov, S S; Motavkin, P A.

Edranov SS; Department of Histology, Vladivostok State Medical University, Russian Ministry of Health, Russia. mobilestom@yandex.ru

Bull Exp Biol Med ; 153(4): 526-9, 2012 Aug.

Article en En, Ru | MEDLINE | ID: mdl-22977862

ABSTRACT

ABSTRACT

Transection of the maxillary nerve initiates apoptosis of the maxillary sinus mucosa cells in rats. Significant activation of apoptosis and proapoptotic factor p53 was found in the epithelium during week 1 after nerve transection. In delayed period after injury, apoptotic cells predominated in the submucosa against the background of Bcl-2 hypoexpression.

Asunto(s)

Apoptosis/fisiología; Nervio Maxilar/fisiopatología; Seno Maxilar/citología; Mucosa Nasal/lesiones; Traumatismos del Nervio Trigémino/fisiopatología; Animales; Inmunohistoquímica; Etiquetado Corte-Fin in Situ; Nervio Maxilar/lesiones; Seno Maxilar/lesiones; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Ratas; Proteína p53 Supresora de Tumor/metabolismo

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Banco de datos: MEDLINE Asunto principal: Apoptosis / Traumatismos del Nervio Trigémino / Nervio Maxilar / Seno Maxilar / Mucosa Nasal Límite: Animals Idioma: En / Ru Año: 2012 Tipo del documento: Article

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