Adsorption of multimeric T cell antigens on carbon nanotubes: effect on protein structure and antigen-specific T cell stimulation.
Small
; 9(5): 666-72, 2013 Mar 11.
Article
en En
| MEDLINE
| ID: mdl-23090793
ABSTRACT
Antigen-specific activation of cytotoxic T cells can be enhanced up to three-fold more than soluble controls when using functionalized bundled carbon nanotube substrates ((b) CNTs). To overcome the denaturing effects of direct adsorption on (b) CNTs, a simple but robust method is demonstrated to stabilize the T cell stimulus on carbon nanotube substrates through non-covalent attachment of the linker neutravidin.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos T
/
Nanotubos de Carbono
/
Antígenos
Límite:
Animals
Idioma:
En
Año:
2013
Tipo del documento:
Article