Spiculisporic acids BD, three new γ-butenolide derivatives from a sea urchin-derived fungus Aspergillus sp. HDf2.
Molecules
; 17(11): 13175-82, 2012 Nov 05.
Article
en En
| MEDLINE
| ID: mdl-23128094
ABSTRACT
Three new γ-butenolide derivatives 1–3, named spiculisporic acids B–D, were isolated from the culture of Aspergillus sp. HDf2, a marine-derived fungus that resides in the sea urchin, Anthocidaris crassispina. The structures of 1–3 were elucidated on the basis of spectroscopic methods, including MS and 2D NMR techniques. Their in vitro cytotoxic activities against two cell lines (SGC-7901, human gastric adenocarcinoma and SPC-A-1, human lung adenocarcinoma) and inhibitory activities against Staphylococcus aureus ATCC 51650 were investigated.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Aspergillus
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Erizos de Mar
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4-Butirolactona
Límite:
Animals
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Humans
Idioma:
En
Año:
2012
Tipo del documento:
Article