Two new diterpenes, neocaesalpin MR and minaxin C, from Caesalpinia minax.

Ma, Guo-Xu; Xu, Na; Yuan, Jing-Quan; Wei, Hua; Zheng, Qing-Xia; Sun, Zhao-Cui; Yang, Jun-Shan; Xu, Xu-Dong

Ma, Guo-Xu; Xu, Na; Yuan, Jing-Quan; Wei, Hua; Zheng, Qing-Xia; Sun, Zhao-Cui; Yang, Jun-Shan; Xu, Xu-Dong.

Ma GX; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China.

J Asian Nat Prod Res ; 14(12): 1156-61, 2012.

Article en En | MEDLINE | ID: mdl-23134417

ABSTRACT

ABSTRACT

Two new cassane-type diterpenes, neocaesalpin MR and minaxin C, were isolated from Caesalpinia minax HANCE. The structures of these compounds were elucidated by means of spectroscopic analysis. Among these isolated compounds, neocaesalpin MR showed mild activities toward HeLa and colon cancer (HCT-8) human cancer cell lines.

Asunto(s)

Antineoplásicos Fitogénicos/aislamiento & purificación; Caesalpinia/química; Diterpenos/aislamiento & purificación; Medicamentos Herbarios Chinos/aislamiento & purificación; Antineoplásicos Fitogénicos/química; Antineoplásicos Fitogénicos/farmacología; Diterpenos/química; Diterpenos/farmacología; Ensayos de Selección de Medicamentos Antitumorales; Medicamentos Herbarios Chinos/química; Medicamentos Herbarios Chinos/farmacología; Humanos; Estructura Molecular; Resonancia Magnética Nuclear Biomolecular

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Caesalpinia / Diterpenos / Antineoplásicos Fitogénicos Límite: Humans Idioma: En Año: 2012 Tipo del documento: Article

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