The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3'-untranslated region:  its role in the efficacy of anti-EGFR-based therapy in metastatic colorectal cancer patients.

Sebio, Ana; Paré, Laia; Páez, David; Salazar, Juliana; González, Alan; Sala, Núria; del Río, Elisabeth; Martín-Richard, Marta; Tobeña, María; Barnadas, Agustí; Baiget, Montserrat

The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3'-untranslated region: its role in the efficacy of anti-EGFR-based therapy in metastatic colorectal cancer patients.

Sebio, Ana; Paré, Laia; Páez, David; Salazar, Juliana; González, Alan; Sala, Núria; del Río, Elisabeth; Martín-Richard, Marta; Tobeña, María; Barnadas, Agustí; Baiget, Montserrat.

Sebio A; Departments of Medical Oncology, Hospital of the Holy Cross and Saint Paul, University Autonoma of Barcelona, Barcelona, Spain.

Pharmacogenet Genomics ; 23(3): 142-7, 2013 Mar.

Article en En | MEDLINE | ID: mdl-23324806

Asunto(s)

Regiones no Traducidas 3'; Neoplasias Colorrectales/tratamiento farmacológico; Receptores ErbB/antagonistas & inhibidores; Genes ras; Polimorfismo de Nucleótido Simple; Sitios de Unión; Neoplasias Colorrectales/genética; Neoplasias Colorrectales/patología; Femenino; Humanos; Masculino; Metástasis de la Neoplasia

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Genes ras / Regiones no Traducidas 3' / Polimorfismo de Nucleótido Simple / Receptores ErbB Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Año: 2013 Tipo del documento: Article

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