[Primitive neuroectodermal tumor/Ewing's sarcoma of the penis in children: a case report and review of the literature].
Zhonghua Nan Ke Xue
; 18(12): 1115-8, 2012 Dec.
Article
en Zh
| MEDLINE
| ID: mdl-23405795
ABSTRACT
OBJECTIVE:
To investigate the clinical manifestations, pathological characteristics and treatment of primitive neuroectodermal tumor/Ewing's sarcoma (PNET/EWS) of the penis in children.METHODS:
We analyzed the clinical data of a case of PNET/EWS and reviewed relevant literature.RESULTS:
The patient was a 5-year-old boy, admitted for penis swelling with pain for 11 months. Biopsy showed a small round cell tumor, CD99 positive by immunohistochemical staining, with EWS translocation by fluorescence in situ hybridization on molecular biological examination. The tumor was confirmed to be PNET/EWS of the penis, and disappeared after 45 weeks of chemotherapy and local radiotherapy.CONCLUSION:
PNET/EWS of the penis is an extremely rare disease, with no specific clinical symptoms except penis enlargement with pain. Immunohistochemistry and molecular biological examination contribute to its diagnosis.
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Banco de datos:
MEDLINE
Asunto principal:
Neoplasias del Pene
/
Sarcoma de Ewing
/
Tumores Neuroectodérmicos Periféricos Primitivos
Límite:
Child, preschool
/
Humans
/
Male
Idioma:
Zh
Año:
2012
Tipo del documento:
Article