General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
J Org Chem
; 78(7): 3208-21, 2013 Apr 05.
Article
en En
| MEDLINE
| ID: mdl-23458237
ABSTRACT
A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Carbohidratos
/
Óxidos de Nitrógeno
Idioma:
En
Año:
2013
Tipo del documento:
Article