Morphological distribution and internal enhancement architecture of contrast-enhanced magnetic resonance imaging in the diagnosis of non-mass-like breast lesions: a meta-analysis.
Breast J
; 19(3): 259-68, 2013.
Article
en En
| MEDLINE
| ID: mdl-23614364
ABSTRACT
The aim of this study is to assess the diagnostic performance of contrast-enhanced magnetic resonance (MR) imaging in patients with non-mass-like breast lesions in a meta-analysis. Literature study was performed on PubMed data base on the diagnostic performance of MR imaging in patients with non-mass-like breast lesions. Details of the relevant studies were reviewed and a meta-analysis was performed to estimate the overall sensitivity and specificity of contrast-enhanced MR imaging of non-mass-like breast lesions. A summary receiver operating characteristic curve (sROC) was developed to explore the threshold effect by ROC space. Spearman correlation coefficient was calculated using Meta-Disc version 1.4 to analyze the heterogeneity between studies. A total of 858 non-mass-like lesions from 15 studies were included in the meta-analysis (sample size range 27-131). Pooled weighted estimates of sensitivity and specificity were 50% (95% CI 46%, 53%) and 80% (95% CI 77%, 83%), respectively. The heterogeneity among studies was caused by other factors other than threshold effect. The findings were influenced by cancer prevalence (p = 0.0359). Subgroup analyses indicated that the sensitivity and specificity in studies with combined diagnostic criterion was higher than that in studies with single diagnostic criterion. In evaluation of non-mass-like breast lesions, contrast-enhanced MRI has high specificity and relatively lower sensitivity.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Mama
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Imagen por Resonancia Magnética
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Aumento de la Imagen
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Medios de Contraste
Tipo de estudio:
Diagnostic_studies
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Prognostic_studies
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Risk_factors_studies
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Systematic_reviews
Límite:
Female
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Humans
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Middle aged
Idioma:
En
Año:
2013
Tipo del documento:
Article