Flexible endoscope for continuous in vivo multispectral fluorescence lifetime imaging.
Opt Lett
; 38(9): 1515-7, 2013 May 01.
Article
en En
| MEDLINE
| ID: mdl-23632536
ABSTRACT
Fluorescence lifetime imaging (FLIM) offers a noninvasive approach for characterizing the biochemical composition of biological tissue. There has been an increasing interest in the application of multispectral FLIM for medical diagnosis. Central to the clinical translation of FLIM technology is the development of compact and high-speed endoscopy systems. Unfortunately, the predominant multispectral FLIM approaches suffer from limitations that impede the development of endoscopy systems that are suitable for in vivo tissue imaging. We present a compact wide-field time-gated FLIM flexible endoscope capable of continuous lifetime imaging of up to three fluorescence emission bands simultaneously. This endoscope design will facilitate the evaluation of FLIM for in vivo applications.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Endoscopios
/
Imagen Molecular
Límite:
Animals
Idioma:
En
Año:
2013
Tipo del documento:
Article