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A phase I first-in-human study with tefinostat - a monocyte/macrophage targeted histone deacetylase inhibitor - in patients with advanced haematological malignancies.
Ossenkoppele, Gert J; Lowenberg, Bob; Zachee, Pierre; Vey, Norbert; Breems, Dimitri; Van de Loosdrecht, Arjan A; Davidson, Alan H; Wells, Graham; Needham, Lindsey; Bawden, Lindsay; Toal, Martin; Hooftman, Leon; Debnam, Phillip M.
  • Ossenkoppele GJ; Department of Haematology, VU University Medical Centre, Amsterdam, The Netherlands.
Br J Haematol ; 162(2): 191-201, 2013 Jul.
Article en En | MEDLINE | ID: mdl-23647373
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monocitos / Neoplasias Hematológicas / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos / Anilidas / Macrófagos Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2013 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monocitos / Neoplasias Hematológicas / Inhibidores de Histona Desacetilasas / Ácidos Hidroxámicos / Anilidas / Macrófagos Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2013 Tipo del documento: Article