A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer.

Morse, Michael A; Niedzwiecki, Donna; Marshall, John L; Garrett, Christopher; Chang, David Z; Aklilu, Mebea; Crocenzi, Todd S; Cole, David J; Dessureault, Sophie; Hobeika, Amy C; Osada, Takuya; Onaitis, Mark; Clary, Bryan M; Hsu, David; Devi, Gayathri R; Bulusu, Anuradha; Annechiarico, Robert P; Chadaram, Vijaya; Clay, Timothy M; Lyerly, H Kim

Morse, Michael A; Niedzwiecki, Donna; Marshall, John L; Garrett, Christopher; Chang, David Z; Aklilu, Mebea; Crocenzi, Todd S; Cole, David J; Dessureault, Sophie; Hobeika, Amy C; Osada, Takuya; Onaitis, Mark; Clary, Bryan M; Hsu, David; Devi, Gayathri R; Bulusu, Anuradha; Annechiarico, Robert P; Chadaram, Vijaya; Clay, Timothy M; Lyerly, H Kim.

Morse MA; Departments of *Medicine, Biostatistics and Bioinformatics, Surgery, Duke University Medical Center §Duke Comprehensive Cancer Center, âDepartment of Immunology, Duke University Medical Center, Durham, NC ¶Georgetown University, Washington, DC **MD Anderson Cancer Center, Houston, TX Wake Forest University Baptist Medical Center, Winston-Salem, NC Earle Chiles Cancer Center, Providence Portland Medical Center, Portland, OR §§Medical University of South Carolina, Charleston, SC ââMoffitt Ca

Ann Surg ; 258(6): 879-86, 2013 Dec.

Article en En | MEDLINE | ID: mdl-23657083

Asunto(s)

Vacunas contra el Cáncer; Antígeno Carcinoembrionario; Neoplasias Colorrectales/prevención & control; Células Dendríticas; Factor Estimulante de Colonias de Granulocitos y Macrófagos; Inmunización/métodos; Glicoproteínas de Membrana; Mucina-1; Recurrencia Local de Neoplasia/prevención & control; Adulto; Anciano; Antígeno Carcinoembrionario/genética; Neoplasias Colorrectales/patología; Neoplasias Colorrectales/cirugía; Supervivencia sin Enfermedad; Femenino; Humanos; Masculino; Persona de Mediana Edad; Mucina-1/genética; Metástasis de la Neoplasia; Poxviridae/genética

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Dendríticas / Glicoproteínas de Membrana / Neoplasias Colorrectales / Antígeno Carcinoembrionario / Factor Estimulante de Colonias de Granulocitos y Macrófagos / Inmunización / Mucina-1 / Vacunas contra el Cáncer / Recurrencia Local de Neoplasia Tipo de estudio: Clinical_trials Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2013 Tipo del documento: Article

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