Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".
Sci Transl Med
; 5(188): 188le2, 2013 Jun 05.
Article
en En
| MEDLINE
| ID: mdl-23740897
ABSTRACT
Egawa et al. recently showed the value of patient-specific induced pluripotent stem cells (iPSCs) for modeling amyotrophic lateral sclerosis in vitro. Their study and our work highlight the need for complementary assays to detect small, but potentially important, phenotypic differences between control iPSC lines and those carrying disease mutations.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Evaluación Preclínica de Medicamentos
/
Células Madre Pluripotentes Inducidas
/
Esclerosis Amiotrófica Lateral
/
Neuronas Motoras
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Año:
2013
Tipo del documento:
Article