Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.
Toxicol Appl Pharmacol
; 272(2): 503-18, 2013 Oct 15.
Article
en En
| MEDLINE
| ID: mdl-23859880
Palabras clave
2,3,7,8-tetracholorodibenzo-p-dioxin; 90-kDa heat shock protein; AHR; AHR-KO; AIP; ALB; ALP; ALT; ARNT; AST; Ahrr; Aryl hydrocarbon receptor knockout mouse; Aryl hydrocarbon receptor knockout rat; BAS; BILI; BLO; BUN; CA; CAOX; CBC; CHOL; CL; CREA; CYP1A1; CYP1A2; CYP1B1; Comparison; DRE; EOS; EPI; GGT; GLOB; GLUC; HB; HBSS; HCT; HSP90; Hank's Balanced Salt Solution; K; KET; Kidney; LD(50); LEUC; LYM; Liver; MCH; MCHC; MCV; MON; NA; NEU; PHOS; PLT; RBC; SG; TBA; TBIL; TCDD; TP; TPHO; TRIG; Tissue phenotypes; UBIL; UGLU; ULEUC; UPRO; URBC; UWBC; WT; ZFN; alanine aminotransferase; alkaline phosphatase; aryl hydrocarbon receptor; aryl hydrocarbon receptor interacting protein; aryl hydrocarbon receptor knockout; aryl hydrocarbon receptor nuclear translocator; aryl hydrocarbon receptor repressor; aspartate aminotransferase; basophils; blood urea nitrogen; calcium; calcium oxalate crystals; chloride; cholesterol; complete blood count; creatinine; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, family 1, subfamily A, polypeptide 2; cytochrome P450, family 1, subfamily B, polypeptide 1; dioxin-response element; eosinophils; hematocrit; hemoglobin; leukocytes; lymphocytes; mean corpuscular hemoglobin; mean corpuscular hemoglobin concentration; mean corpuscular volume; median lethal dose; monocytes; neutrophils; phosphorus; platelets; potassium; red blood cells; serum albumin; serum globulin; serum glucose; sodium; total bile acid; total bilirubin; total serum protein; total white blood cells; triglycerides; triple phosphate crystals; urine bilinogen; urine bilirubin; urine epithelial cells; urine glucose; urine ketones; urine leukocytes; urine occult blood; urine protein; urine red blood cells; urine specific gravity; wild-type; zinc finger nuclease; γ-glutamyl transpeptidase
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Eliminación de Gen
/
Receptores de Hidrocarburo de Aril
/
Dibenzodioxinas Policloradas
/
Riñón
/
Hígado
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Año:
2013
Tipo del documento:
Article