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Dose metric considerations in in vitro assays to improve quantitative in vitro-in vivo dose extrapolations.
Groothuis, Floris A; Heringa, Minne B; Nicol, Beate; Hermens, Joop L M; Blaauboer, Bas J; Kramer, Nynke I.
  • Groothuis FA; Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands. Electronic address: f.a.groothuis@uu.nl.
  • Heringa MB; National Institute of Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands. Electronic address: minne.heringa@rivm.nl.
  • Nicol B; Unilever U.K., Safety & Environmental Assurance Centre, Colworth Science Park, Sharnbrook, Bedford MK44 1LQ, United Kingdom. Electronic address: Beate.Nicol@unilever.com.
  • Hermens JL; Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands. Electronic address: j.hermens@uu.nl.
  • Blaauboer BJ; Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands. Electronic address: b.blaauboer@uu.nl.
  • Kramer NI; Institute for Risk Assessment Sciences, Utrecht University, PO Box 80177, 3508 TD Utrecht, The Netherlands. Electronic address: N.I.Kramer@uu.nl.
Toxicology ; 332: 30-40, 2015 Jun 05.
Article en En | MEDLINE | ID: mdl-23978460
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxicología / Técnicas In Vitro / Pruebas de Toxicidad / Relación Dosis-Respuesta a Droga / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Toxicología / Técnicas In Vitro / Pruebas de Toxicidad / Relación Dosis-Respuesta a Droga / Modelos Biológicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Año: 2015 Tipo del documento: Article