TRIM13 regulates caspase-8 ubiquitination, translocation to autophagosomes and activation during ER stress induced cell death.

Tomar, Dhanendra; Prajapati, Paresh; Sripada, Lakshmi; Singh, Kritarth; Singh, Rochika; Singh, Arun Kumar; Singh, Rajesh

Tomar, Dhanendra; Prajapati, Paresh; Sripada, Lakshmi; Singh, Kritarth; Singh, Rochika; Singh, Arun Kumar; Singh, Rajesh.

Tomar D; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Prajapati P; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Sripada L; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Singh K; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Singh R; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Singh AK; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
Singh R; Department of Cell Biology, School of Biological Sciences and Biotechnology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India. Electronic address: rsingh@iiar.res.in.

Biochim Biophys Acta ; 1833(12): 3134-3144, 2013 Dec.

Article en En | MEDLINE | ID: mdl-24021263

Asunto(s)

Caspasa 8/metabolismo; Proteínas de Unión al ADN/metabolismo; Estrés del Retículo Endoplásmico; Fagosomas/metabolismo; Proteínas Supresoras de Tumor/metabolismo; Ubiquitinación; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Autofagia/efectos de los fármacos; Estrés del Retículo Endoplásmico/efectos de los fármacos; Activación Enzimática/efectos de los fármacos; Células HEK293; Humanos; Lisosomas/efectos de los fármacos; Lisosomas/metabolismo; Células MCF-7; Fagosomas/efectos de los fármacos; Transporte de Proteínas/efectos de los fármacos; Factores de Transcripción del Factor Regulador X; Proteína Sequestosoma-1; Transducción de Señal/efectos de los fármacos; Factores de Transcripción/metabolismo; Tunicamicina/farmacología; Ubiquitinación/efectos de los fármacos; Respuesta de Proteína Desplegada/efectos de los fármacos

Palabras clave

Autophagy; Caspase-8; Cell death; Endoplasmic reticulum stress; TRIM13; Ubiquitin ligase

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fagosomas / Proteínas Supresoras de Tumor / Proteínas de Unión al ADN / Caspasa 8 / Ubiquitinación / Estrés del Retículo Endoplásmico Límite: Humans Idioma: En Año: 2013 Tipo del documento: Article

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