Detection of Borrelia burgdorferi DNA in museum specimens of Ixodes dammini ticks.
Science
; 249(4975): 1420-3, 1990 Sep 21.
Article
en En
| MEDLINE
| ID: mdl-2402635
ABSTRACT
In order to investigate the potential for Borrelia burgdorferi infection before the recognition of Lyme disease as a clinical entity, the polymerase chain reaction (PCR) was used to examine museum specimens of Ixodes dammini (deer ticks) for the presence of spirochete-specific DNA sequences. One hundred and thirty-six archival tick specimens were obtained representing various continental U.S. locations; DNA sequences characteristic of modern day isolates of B. burgdorferi were detected in 13 1940s specimens from Montauk Point and Hither Hills, Long Island, New York. Five archival specimens of Dermacentor variabilis (dog tick) from the same collection and 118 Ixodes specimens from other endemic and nonendemic sites were negative. These data suggest that the appearance of the Lyme disease spirochete in suitable arthropod vectors preceded, by at least a generation, the formal recognition of this disease as a clinical entity in the United States.
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Banco de datos:
MEDLINE
Asunto principal:
Garrapatas
/
ADN Bacteriano
/
Grupo Borrelia Burgdorferi
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
/
Humans
País como asunto:
America do norte
Idioma:
En
Año:
1990
Tipo del documento:
Article