Synthesis, antibacterial, and antiviral evaluation of new heterocycles containing the pyridine moiety.
Arch Pharm (Weinheim)
; 346(10): 766-73, 2013 Oct.
Article
en En
| MEDLINE
| ID: mdl-24105721
ABSTRACT
A facile one-pot four-component reaction was utilized to construct 2-oxo-1,2-dihydropyridine-3-carbonitrile as a scaffold for the synthesis of many fused heterocyclic systems, namely, furopyridine, pyridothiadiazepinthione, and pyridotriazine, as well as non-fused heterocyclic systems such as phthalazin-2(1H)-ylnicotinonitrile, pyridin-2-yl-1H-pyrazole, and pyrazol-1-ylnicotino-nitrile,1-(3-cyanopyridin-2-yl)-1H-pyrazole. The new compounds were evaluated as antimicrobial and antiviral agents.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Antivirales
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Piridinas
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Compuestos Heterocíclicos
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Antibacterianos
Límite:
Animals
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Humans
Idioma:
En
Año:
2013
Tipo del documento:
Article