Investigation of 5-HT4 receptors in bronchial hyperresponsiveness in cigarette smoke-exposed mice.

Dupont, Lisa L; Bracke, Ken R; De Maeyer, Joris H; Compan, Valérie; Joos, Guy F; Lefebvre, Romain A; Brusselle, Guy G

Dupont, Lisa L; Bracke, Ken R; De Maeyer, Joris H; Compan, Valérie; Joos, Guy F; Lefebvre, Romain A; Brusselle, Guy G.

Dupont LL; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: lisa.dupont@ugent.be.
Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: ken.bracke@ugent.be.
De Maeyer JH; Shire-Movetis NV, Turnhout, Belgium. Electronic address: joris.demaeyer@outlook.com.
Compan V; CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, France; INSERM, U661, Montpellier, France; Universités de Montpellier 1 & 2, UMR-5203, Montpellier, France; Université de Nîmes, Nîmes, France. Electronic address: valerie.compan@igf.cnrs.fr.
Joos GF; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: guy.joos@ugent.be.
Lefebvre RA; Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium. Electronic address: romain.lefebvre@ugent.be.
Brusselle GG; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address: guy.brusselle@ugent.be.

Pulm Pharmacol Ther ; 28(1): 60-67, 2014 Jun.

Article en En | MEDLINE | ID: mdl-24183679

Asunto(s)

Hiperreactividad Bronquial/fisiopatología; Enfermedad Pulmonar Obstructiva Crónica/fisiopatología; Receptores de Serotonina 5-HT4/genética; Contaminación por Humo de Tabaco/efectos adversos; Animales; Hiperreactividad Bronquial/genética; Broncoconstricción/genética; Modelos Animales de Enfermedad; Indoles/farmacología; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Enfermedad Pulmonar Obstructiva Crónica/etiología; Enfermedad Pulmonar Obstructiva Crónica/genética; ARN Mensajero/metabolismo; Receptor de Serotonina 5-HT2A/metabolismo; Receptores Muscarínicos/metabolismo; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Sulfonamidas/farmacología

Palabras clave

COPD; Cigarette smoke; Murine model; Serotonin 4 receptors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Contaminación por Humo de Tabaco / Hiperreactividad Bronquial / Enfermedad Pulmonar Obstructiva Crónica / Receptores de Serotonina 5-HT4 Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article

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