An unusual association between acute ischaemic stroke and cerebral venous thrombosis with thyrotoxic state.
BMJ Case Rep
; 20132013 Dec 05.
Article
en En
| MEDLINE
| ID: mdl-24311416
ABSTRACT
Arterial cerebral ischaemia has been described in different diseases of the thyroid. Likewise, cerebral venous thrombosis (CVT) has been reported in association with hyperthyroidism. However, the association of arterial and venous cerebral ischaemic events in patients with hyperthyroidism has not been previously described. We report the case of a patient with thyrotoxicosis who presented initially with an arterial ischaemic stroke complicated by a concomitant CVT, ultimately treated with decompressive craniectomy. Laboratory results revealed elevated factor VIII coagulant activity and a positive lupus anticoagulant IgG. In conclusion, CVT and arterial ischaemic events can happen concomitantly in patients with hyperthyroidism. Although there is insufficient evidence to prove that a hypercoagulability state in hyperthyroidism predisposes to cerebral ischaemia, the presence of antiphospholipid antibodies and other hypercoagulability studies should be performed in patients with thyrotoxicosis and ischaemic events.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Tirotoxicosis
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Accidente Cerebrovascular
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Trombosis Intracraneal
Tipo de estudio:
Diagnostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Año:
2013
Tipo del documento:
Article