Discovery and saturation analysis of cancer genes across 21 tumour types.

Lawrence, Michael S; Stojanov, Petar; Mermel, Craig H; Robinson, James T; Garraway, Levi A; Golub, Todd R; Meyerson, Matthew; Gabriel, Stacey B; Lander, Eric S; Getz, Gad

Lawrence, Michael S; Stojanov, Petar; Mermel, Craig H; Robinson, James T; Garraway, Levi A; Golub, Todd R; Meyerson, Matthew; Gabriel, Stacey B; Lander, Eric S; Getz, Gad.

Lawrence MS; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Stojanov P; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
Mermel CH; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Massachusetts General Hospital, Cancer Center and Department of Pathology, 55 Fruit Street, Boston, Massachusetts 02114, USA.
Robinson JT; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Garraway LA; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA.
Golub TR; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA [4] Howard Hughes Medical Institute
Meyerson M; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02215, USA [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA.
Gabriel SB; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.
Lander ES; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115, USA [3] Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA [4].
Getz G; 1] Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA [2] Massachusetts General Hospital, Cancer Center and Department of Pathology, 55 Fruit Street, Boston, Massachusetts 02114, USA [3] Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115,

Nature ; 505(7484): 495-501, 2014 Jan 23.

Article en En | MEDLINE | ID: mdl-24390350

Asunto(s)

Genes Relacionados con las Neoplasias/genética; Neoplasias/clasificación; Neoplasias/genética; Apoptosis/genética; Estudios de Casos y Controles; Proliferación Celular; Cromatina/genética; Análisis Mutacional de ADN; Exoma/genética; Genoma Humano/genética; Inestabilidad Genómica/genética; Genómica; Humanos; Evasión Inmune/genética; Tasa de Mutación; Neoplasias/patología; Mutación Puntual/genética; Procesamiento Postranscripcional del ARN/genética; Tamaño de la Muestra

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genes Relacionados con las Neoplasias / Neoplasias Tipo de estudio: Observational_studies Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article

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