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Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Cohen, Paul; Levy, Julia D; Zhang, Yingying; Frontini, Andrea; Kolodin, Dmitriy P; Svensson, Katrin J; Lo, James C; Zeng, Xing; Ye, Li; Khandekar, Melin J; Wu, Jun; Gunawardana, Subhadra C; Banks, Alexander S; Camporez, João Paulo G; Jurczak, Michael J; Kajimura, Shingo; Piston, David W; Mathis, Diane; Cinti, Saverio; Shulman, Gerald I; Seale, Patrick; Spiegelman, Bruce M.
  • Cohen P; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Levy JD; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Zhang Y; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Frontini A; Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona 60020, Italy.
  • Kolodin DP; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Svensson KJ; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Lo JC; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Zeng X; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Ye L; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Khandekar MJ; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Wu J; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Gunawardana SC; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
  • Banks AS; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
  • Camporez JP; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
  • Jurczak MJ; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA.
  • Kajimura S; UCSF Diabetes Center and Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, CA 94143, USA.
  • Piston DW; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA.
  • Mathis D; Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  • Cinti S; Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, Ancona 60020, Italy.
  • Shulman GI; Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Cellular and Molecular Physiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06519, USA.
  • Seale P; Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Spiegelman BM; Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA. Electronic address: bruce_spiegelman@dfci.harvard.edu.
Cell ; 156(1-2): 304-16, 2014 Jan 16.
Article en En | MEDLINE | ID: mdl-24439384

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Tejido Adiposo Pardo / Tejido Adiposo / Proteínas de Unión al ADN / Obesidad Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Tejido Adiposo Pardo / Tejido Adiposo / Proteínas de Unión al ADN / Obesidad Tipo de estudio: Etiology_studies Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article