AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor.

Chen, Shiuan; Zhou, Dujin; Hsin, Li-Yu; Kanaya, Noriko; Wong, Cynthie; Yip, Richard; Sakamuru, Srilatha; Xia, Menghang; Yuan, Yate-Ching; Witt, Kristine; Teng, Christina

Chen, Shiuan; Zhou, Dujin; Hsin, Li-Yu; Kanaya, Noriko; Wong, Cynthie; Yip, Richard; Sakamuru, Srilatha; Xia, Menghang; Yuan, Yate-Ching; Witt, Kristine; Teng, Christina.

Chen S; Department of Cancer Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010.

Toxicol Sci ; 139(1): 198-209, 2014 May.

Article en En | MEDLINE | ID: mdl-24496634

Asunto(s)

Aromatasa/efectos de los fármacos; Disruptores Endocrinos/toxicidad; Receptores de Estrógenos/efectos de los fármacos; Secuencia de Bases; Cartilla de ADN; Humanos; Células MCF-7

Palabras clave

Aromatase-expressing cell line; EDCs; MCF-7 cells; Tox21; estrogen receptor; high-throughput screening; qHTS

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Aromatasa / Receptores de Estrógenos / Disruptores Endocrinos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article

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