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Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer.
Saunders, Edward J; Dadaev, Tokhir; Leongamornlert, Daniel A; Jugurnauth-Little, Sarah; Tymrakiewicz, Malgorzata; Wiklund, Fredrik; Al Olama, Ali Amin; Benlloch, Sara; Neal, David E; Hamdy, Freddie C; Donovan, Jenny L; Giles, Graham G; Severi, Gianluca; Gronberg, Henrik; Aly, Markus; Haiman, Christopher A; Schumacher, Fredrick; Henderson, Brian E; Lindstrom, Sara; Kraft, Peter; Hunter, David J; Gapstur, Susan; Chanock, Stephen; Berndt, Sonja I; Albanes, Demetrius; Andriole, Gerald; Schleutker, Johanna; Weischer, Maren; Nordestgaard, Børge G; Canzian, Federico; Campa, Daniele; Riboli, Elio; Key, Tim J; Travis, Ruth C; Ingles, Sue A; John, Esther M; Hayes, Richard B; Pharoah, Paul; Khaw, Kay-Tee; Stanford, Janet L; Ostrander, Elaine A; Signorello, Lisa B; Thibodeau, Stephen N; Schaid, Daniel; Maier, Christiane; Kibel, Adam S; Cybulski, Cezary; Cannon-Albright, Lisa; Brenner, Hermann; Park, Jong Y.
  • Saunders EJ; The Institute of Cancer Research, Sutton, Surrey, United Kingdom.
  • Dadaev T; The Institute of Cancer Research, Sutton, Surrey, United Kingdom.
  • Leongamornlert DA; The Institute of Cancer Research, Sutton, Surrey, United Kingdom.
  • Jugurnauth-Little S; The Institute of Cancer Research, Sutton, Surrey, United Kingdom.
  • Tymrakiewicz M; The Institute of Cancer Research, Sutton, Surrey, United Kingdom.
  • Wiklund F; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
  • Al Olama AA; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Laboratory, Cambridge, United Kingdom.
  • Benlloch S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Laboratory, Cambridge, United Kingdom.
  • Neal DE; Surgical Oncology (Uro-Oncology: S4), University of Cambridge, Addenbrooke's Hospital, Cambridge and Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Cambridge, United Kingdom.
  • Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, and Faculty of Medical Science, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
  • Donovan JL; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
  • Giles GG; Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria, Australia and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia.
  • Severi G; Cancer Epidemiology Centre, The Cancer Council Victoria, Carlton, Victoria, Australia and Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, The University of Melbourne, Melbourne, Victoria, Australia.
  • Gronberg H; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
  • Aly M; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
  • Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Schumacher F; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Henderson BE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • Lindstrom S; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.
  • Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.
  • Hunter DJ; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America.
  • Gapstur S; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America.
  • Chanock S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, United States of America.
  • Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, United States of America.
  • Albanes D; Nutritional Epidemiology Branch, National Cancer Institute, NIH, EPS-3044, Bethesda, Maryland, United States of America.
  • Andriole G; Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America.
  • Schleutker J; Department of Medic Biochemistry and Genetics, University of Turku, Turku and Institute of Biomedical Technology and BioMediTech, University of Tampere and FimLab Laboratories, Tampere, Finland.
  • Weischer M; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark.
  • Nordestgaard BG; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark.
  • Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Campa D; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Riboli E; Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
  • Key TJ; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
  • Travis RC; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.
  • Ingles SA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, United States of America.
  • John EM; Cancer Prevention Institute of California, Fremont, California, United States of America, and Stanford University School of Medicine, Stanford, California, United States of America.
  • Hayes RB; Division of Epidemiology, Department of Population Health, NYU Langone Medical Center, NYU Cancer Institute, New York, New York, United States of America.
  • Pharoah P; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Laboratory, Cambridge, United Kingdom.
  • Khaw KT; Clinical Gerontology Unit, University of Cambridge, Cambridge, United Kingdom.
  • Stanford JL; Department of Epidemiology, School of Public Health, University of Washington and Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Ostrander EA; National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Signorello LB; International Epidemiology Institute, Rockville, Maryland, and Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.
  • Thibodeau SN; Mayo Clinic, Rochester, Minnesota, United States of America.
  • Schaid D; Mayo Clinic, Rochester, Minnesota, United States of America.
  • Maier C; Department of Urology, University Hospital Ulm and Institute of Human Genetics University Hospital Ulm, Ulm, Germany.
  • Kibel AS; Division of Urologic Surgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.
  • Cybulski C; International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
  • Cannon-Albright L; Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine and George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, United States of America.
  • Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Park JY; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center, Tampa, Florida, United States of America.
PLoS Genet ; 10(2): e1004129, 2014 Feb.
Article en En | MEDLINE | ID: mdl-24550738
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Variación Genética / Proteínas de Homeodominio / Predisposición Genética a la Enfermedad Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Variación Genética / Proteínas de Homeodominio / Predisposición Genética a la Enfermedad Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Año: 2014 Tipo del documento: Article