The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease.

Beaumont, Vahri; Park, Larry; Rassoulpour, Arash; Dijkman, Ulrike; Heikkinen, Taneli; Lehtimaki, Kimmo; Kontkanen, Outi; Al Nackkash, Rand; Bates, Gillian P; Gleyzes, Melanie; Steidl, Esther; Ramboz, Sylvie; Murphy, Carol; Beconi, Maria G; Dominguez, Celia; Munoz-Sanjuan, Ignacio.

Beaumont V; CHDI Management/CHDI Foundation, Los Angeles, California, USA.
Park L; CHDI Management/CHDI Foundation, Los Angeles, California, USA.
Rassoulpour A; Brains On-Line LLC, South San Francisco, California, USA.
Dijkman U; Brains On-Line LLC, South San Francisco, California, USA.
Heikkinen T; Charles River Discovery Research Services, Kuopio, Finland.
Lehtimaki K; Charles River Discovery Research Services, Kuopio, Finland.
Kontkanen O; Charles River Discovery Research Services, Kuopio, Finland.
Al Nackkash R; Department of Medical and Molecular Genetics, Kings College London, London, UK.
Bates GP; Department of Medical and Molecular Genetics, Kings College London, London, UK.
Gleyzes M; Neuroservice, Domaine de Saint Hilaire, 13593 Aix en Provence cedex 03, France.
Steidl E; Neuroservice, Domaine de Saint Hilaire, 13593 Aix en Provence cedex 03, France.
Ramboz S; PsychoGenics Inc., Tarrytown, New York, USA.
Murphy C; PsychoGenics Inc., Tarrytown, New York, USA.
Beconi MG; CHDI Management/CHDI Foundation, Los Angeles, California, USA.
Dominguez C; CHDI Management/CHDI Foundation, Los Angeles, California, USA.
Munoz-Sanjuan I; CHDI Management/CHDI Foundation, Los Angeles, California, USA.

PLoS Curr ; 62014 Feb 13.

Article en En | MEDLINE | ID: mdl-24558637

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2014 Tipo del documento: Article