A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis.

Williams, Sunanda Margrett; Chandran, Anu V; Vijayabaskar, Mahalingam S; Roy, Sourav; Balaram, Hemalatha; Vishveshwara, Saraswathi; Vijayan, Mamannamana; Chatterji, Dipankar

Williams, Sunanda Margrett; Chandran, Anu V; Vijayabaskar, Mahalingam S; Roy, Sourav; Balaram, Hemalatha; Vishveshwara, Saraswathi; Vijayan, Mamannamana; Chatterji, Dipankar.

Williams SM; Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Chandran AV; Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Vijayabaskar MS; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom, and.
Roy S; Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560 064, India.
Balaram H; Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560 064, India.
Vishveshwara S; Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Vijayan M; Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Chatterji D; Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India,; Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560 064, India. Electronic address: dipankar@mbu.iisc.ernet.in.

J Biol Chem ; 289(16): 11042-11058, 2014 Apr 18.

Article en En | MEDLINE | ID: mdl-24573673

Asunto(s)

Proteínas Bacterianas/química; Ferritinas/química; Hierro/química; Mycobacterium smegmatis/química; Ácido Aspártico/química; Ácido Aspártico/genética; Ácido Aspártico/metabolismo; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Transporte Biológico Activo/fisiología; Cristalografía por Rayos X; Ferritinas/genética; Ferritinas/inmunología; Histidina/química; Histidina/genética; Histidina/metabolismo; Hierro/metabolismo; Mycobacterium smegmatis/genética; Mycobacterium smegmatis/metabolismo; Estructura Terciaria de Proteína; Relación Estructura-Actividad

Palabras clave

DNA-binding Protein; Ion Channels; Ionic Cluster; Iron; Iron Oxidation; Mycobacterium; Mycobacterium smegmatis; X-ray Crystallography

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Mycobacterium smegmatis / Ferritinas / Hierro Tipo de estudio: Prognostic_studies Idioma: En Año: 2014 Tipo del documento: Article

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