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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry.
Regalado, Erik L; Kozlowski, Marisa C; Curto, John M; Ritter, Tobias; Campbell, Michael G; Mazzotti, Anthony R; Hamper, Bruce C; Spilling, Christopher D; Mannino, Michael P; Wan, Li; Yu, Jin-Quan; Liu, Jinchu; Welch, Christopher J.
  • Regalado EL; Merck Research Laboratories, Rahway, New Jersey 07065, USA. christopher_welch@merck.com erik.regalado@merck.com.
Org Biomol Chem ; 12(14): 2161-6, 2014 Apr 14.
Article en En | MEDLINE | ID: mdl-24589831
ABSTRACT
The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Compuestos Orgánicos / Industria Farmacéutica / Fraccionamiento Químico Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Compuestos Orgánicos / Industria Farmacéutica / Fraccionamiento Químico Idioma: En Año: 2014 Tipo del documento: Article