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[Rechallenge of everolimus for metastatic renal cell carcinoma after recovery from grade 3 interstitial lung disease: a case report].
Utsunomiya, Noriaki; Kono, Yuka; Matsumoto, Keiyu; Matsumoto, Takeshi; Nakagawa, Atsushi; Tsunemori, Hiroyuki; Okada, Takuya; Muguruma, Koei; Kawakita, Mutsushi.
  • Utsunomiya N; The Department of Urology, Kobe City Medical Center General Hospital.
  • Kono Y; The Department of Urology, Kobe City Medical Center General Hospital.
  • Matsumoto K; The Department of Urology, Kobe City Medical Center General Hospital.
  • Matsumoto T; The Department of Respiratory Medicine, Kobe City Medical Center General Hospital.
  • Nakagawa A; The Department of Respiratory Medicine, Kobe City Medical Center General Hospital.
  • Tsunemori H; The Department of Urology, Kobe City Medical Center General Hospital.
  • Okada T; The Department of Urology, Kobe City Medical Center General Hospital.
  • Muguruma K; The Department of Urology, Kobe City Medical Center General Hospital.
  • Kawakita M; The Department of Urology, Kobe City Medical Center General Hospital.
Hinyokika Kiyo ; 60(1): 25-8, 2014 Jan.
Article en Ja | MEDLINE | ID: mdl-24594769
ABSTRACT
We report a case of the rechallenge of everolimus for metastatic renal cell carcinoma (RCC) after successful recovery from grade 3 interstitial lung disease (ILD). A 76-year-old man with metastatic RCC developed grade 3 ILD one month after the initiation of everolimus therapy (10 mg/day). ILD subsided in 4 months after the withdrawal of everolimus and treatment with corticosteroids. Half dose (5 mg/day) of everolimus was rechallenged for 9 months until another grade 3 ILD developed. Everolimus kept the disease under control for 13 months including the discontinuation period.
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Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Enfermedades Pulmonares Intersticiales / Sirolimus / Inhibidores Enzimáticos / Serina-Treonina Quinasas TOR / Neoplasias Renales / Antineoplásicos Límite: Aged / Humans / Male Idioma: Ja Año: 2014 Tipo del documento: Article
Search on Google
Imprimir
XML
PubMed Links

Banco de datos: MEDLINE Asunto principal: Carcinoma de Células Renales / Enfermedades Pulmonares Intersticiales / Sirolimus / Inhibidores Enzimáticos / Serina-Treonina Quinasas TOR / Neoplasias Renales / Antineoplásicos Límite: Aged / Humans / Male Idioma: Ja Año: 2014 Tipo del documento: Article