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Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
Fairfax, Benjamin P; Humburg, Peter; Makino, Seiko; Naranbhai, Vivek; Wong, Daniel; Lau, Evelyn; Jostins, Luke; Plant, Katharine; Andrews, Robert; McGee, Chris; Knight, Julian C.
  • Fairfax BP; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Humburg P; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Makino S; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Naranbhai V; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Wong D; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Lau E; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Jostins L; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Plant K; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
  • Andrews R; Wellcome Trust Sanger Institute, University of Cambridge, Hinxton CB10 1SA, UK.
  • McGee C; Wellcome Trust Sanger Institute, University of Cambridge, Hinxton CB10 1SA, UK.
  • Knight JC; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK.
Science ; 343(6175): 1246949, 2014 Mar 07.
Article en En | MEDLINE | ID: mdl-24604202

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monocitos / Enfermedad de Crohn / Regulación de la Expresión Génica / Predisposición Genética a la Enfermedad / Inmunidad Innata Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Monocitos / Enfermedad de Crohn / Regulación de la Expresión Génica / Predisposición Genética a la Enfermedad / Inmunidad Innata Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2014 Tipo del documento: Article