Heterogeneous anomalous diffusion of a virus in the cytoplasm of a living cell.
J Biol Phys
; 38(4): 673-9, 2012 Sep.
Article
en En
| MEDLINE
| ID: mdl-24615226
ABSTRACT
The infection pathway of a virus in the cytoplasm of a living cell is studied from the viewpoint of diffusion theory, based on a phenomenon observed by single-molecule imaging. The cytoplasm plays the role of a medium for stochastic motion of a virus contained in an endosome as well as a free virus. It is experimentally known that the exponent of anomalous diffusion fluctuates in localized areas of the cytoplasm. Here, generalizing the fractional kinetic theory, such fluctuations are described in terms of the exponent locally distributed over the cytoplasm and a theoretical proposition is presented for its statistical form. The proposed fluctuations may be examined in an experiment of heterogeneous diffusion in the infection pathway.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Dependovirus
/
Citoplasma
Límite:
Humans
Idioma:
En
Año:
2012
Tipo del documento:
Article