Absence of obesity paradox in Saudi patients admitted with acute coronary syndromes: insights from SPACE registry.
Ann Saudi Med
; 34(1): 38-45, 2014.
Article
en En
| MEDLINE
| ID: mdl-24658552
ABSTRACT
BACKGROUND AND OBJECTIVES:
To describe the distribution of body mass index (BMI) and its relationship with clinical features, management, and in-hospital outcomes of patients admitted with acute coronary syndromes (ACS). DESIGN AND SETTINGS The Saudi Project for Assessment of Coronary Events is a prospective registry. ACS patients admitted to 17 hospitals from December 2005-2007 were included in this study.METHODS:
BMI was available for 3469 patients (68.6%) admitted with ACS and categorized into 4 groups normal weight, overweight, obese, and morbidly obese.RESULTS:
Of patients admitted with ACS, 72% were either overweight or obese. A high prevalence of diabetes (57%), hypertension (56.6%), dyslipidemia (42%), and smoking (32.4%) was reported. Increasing BMI was significantly associated with diabetes, hypertension, and hyperlipidemia. Overweight and obese patients were significantly younger than the normal-weight group (P=.006). However, normal-weight patients were more likely to be smokers and had 3-vessel coronary artery disease, worse left ventricular dysfunction, and ST elevation myocardial infarction. Glycoprotein IIb-IIIa antagonists were used significantly more in overweight, obese, and morbidly obese ACS patients than in normal-weight patients (P≤.001). Coronary angiography and percutaneous intervention were reported more in overweight and obese patients than in normal-weight patients (P≤.001). In-hospital outcomes were not significantly different among the BMI categories.CONCLUSION:
High BMI is prevalent among Saudi patients with ACS. BMI was not an independent factor for in-hospital outcomes. In contrast with previous reports, high BMI was not associated with improved outcomes, indicating the absence of obesity paradox observed in other studies.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Índice de Masa Corporal
/
Distribuciones Estadísticas
/
Síndrome Coronario Agudo
/
Obesidad
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Female
/
Humans
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Male
/
Middle aged
País como asunto:
Asia
Idioma:
En
Año:
2014
Tipo del documento:
Article