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All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.
Sawada, Osamu; Perusek, Lindsay; Kohno, Hideo; Howell, Scott J; Maeda, Akiko; Matsuyama, Shigemi; Maeda, Tadao.
  • Sawada O; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA; Ophthalmology, Shiga University of Medical Science, Otsu, Shiga 520-2192, Japan.
  • Perusek L; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA.
  • Kohno H; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA; Ophthalmology, Jikei University School of Medicine, Minato-ku, Tokyo 105-8461, Japan.
  • Howell SJ; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA.
  • Maeda A; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA; Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
  • Matsuyama S; Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA; Medicine, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA.
  • Maeda T; Ophthalmology and Visual Sciences, School of Medicine, Case Western Reserve University, Adelbert Road 2085, Cleveland, OH 44106, USA; Pharmacology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: tadao.maeda@gmail.com.
Exp Eye Res ; 123: 27-36, 2014 Jun.
Article en En | MEDLINE | ID: mdl-24726920

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Retina / Retinaldehído / Daño del ADN / Apoptosis / Proteína X Asociada a bcl-2 / Epitelio Pigmentado de la Retina Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Retina / Retinaldehído / Daño del ADN / Apoptosis / Proteína X Asociada a bcl-2 / Epitelio Pigmentado de la Retina Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article