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Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.
Rampal, Raajit; Al-Shahrour, Fatima; Abdel-Wahab, Omar; Patel, Jay P; Brunel, Jean-Philippe; Mermel, Craig H; Bass, Adam J; Pretz, Jennifer; Ahn, Jihae; Hricik, Todd; Kilpivaara, Outi; Wadleigh, Martha; Busque, Lambert; Gilliland, D Gary; Golub, Todd R; Ebert, Benjamin L; Levine, Ross L.
  • Rampal R; Human Oncology and Pathogenesis Program, and Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY;
  • Al-Shahrour F; Translational Bioinformatics Unit, Clinical Research Programme, Spanish National Cancer Research Centre, Madrid, Spain;
  • Abdel-Wahab O; Human Oncology and Pathogenesis Program, and Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY;
  • Patel JP; Human Oncology and Pathogenesis Program, and.
  • Brunel JP; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA;
  • Mermel CH; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Massachusetts General Hospital, Cancer Center and Department of Pathology, Boston, MA;
  • Bass AJ; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Dana-Farber Cancer Institute, Boston, MA;
  • Pretz J; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Dana-Farber Cancer Institute, Boston, MA;
  • Ahn J; Human Oncology and Pathogenesis Program, and.
  • Hricik T; Human Oncology and Pathogenesis Program, and.
  • Kilpivaara O; Department of Medical Genetics, Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland;
  • Wadleigh M; Dana-Farber Cancer Institute, Boston, MA;
  • Busque L; Research Centre, Maisonneuve-Rosemont Hospital, Department of Hematology, Maisonneuve-Rosemont Hospital, and University of Montreal, Montreal, QC, Canada;
  • Gilliland DG; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;
  • Golub TR; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Children's Hospital, Harvard Medical School, Boston, MA; Howard Hughes Medical Institute, Chevy Chase, MD; and.
  • Ebert BL; Broad Institute of Harvard University and the Massachusetts Institute of Technology, Cambridge, MA; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Levine RL; Human Oncology and Pathogenesis Program, and Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY; Weill Cornell Medical College, New York, NY;
Blood ; 123(22): e123-33, 2014 May 29.
Article en En | MEDLINE | ID: mdl-24740812

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Genómica / Factores de Transcripción STAT / Quinasas Janus / Trastornos Mieloproliferativos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Año: 2014 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Genómica / Factores de Transcripción STAT / Quinasas Janus / Trastornos Mieloproliferativos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies Límite: Female / Humans / Male Idioma: En Año: 2014 Tipo del documento: Article