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Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly.
Abdi, Kaveh; Singh, Nevil J; Spooner, Eric; Kessler, Benedikt M; Radaev, Sergei; Lantz, Larry; Xiao, Tsan Sam; Matzinger, Polly; Sun, Peter D; Ploegh, Hidde L.
  • Abdi K; Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; kabdi@niaid.nih.gov.
  • Singh NJ; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;
  • Spooner E; Whitehead Institute for Biomedical Research, Cambridge, MA 02142;
  • Kessler BM; Target Discovery Institute, Nuffield Department of Clinical Medicine, Oxford University, Oxford OX3 7FZ, United Kingdom;
  • Radaev S; Resources and Training Review Branch, National Cancer Institute, Bethesda, MD 20892;
  • Lantz L; Research Technology Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852;
  • Xiao TS; Structural Immunobiology Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.
  • Matzinger P; Laboratory of Cellular and Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892;
  • Sun PD; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
  • Ploegh HL; Whitehead Institute for Biomedical Research, Cambridge, MA 02142;
J Immunol ; 192(12): 6028-36, 2014 Jun 15.
Article en En | MEDLINE | ID: mdl-24821971
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Interleucina-12 / Dimerización / Proteínas Reguladoras de la Apoptosis Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Interleucina-12 / Dimerización / Proteínas Reguladoras de la Apoptosis Límite: Animals Idioma: En Año: 2014 Tipo del documento: Article