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Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.
Naganawa, Mika; Jacobsen, Leslie K; Zheng, Ming-Qiang; Lin, Shu-Fei; Banerjee, Anindita; Byon, Wonkyung; Weinzimmer, David; Tomasi, Giampaolo; Nabulsi, Nabeel; Grimwood, Sarah; Badura, Lori L; Carson, Richard E; McCarthy, Timothy J; Huang, Yiyun.
  • Naganawa M; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA. Electronic address: mika.naganawa@yale.edu.
  • Jacobsen LK; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Zheng MQ; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Lin SF; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Banerjee A; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Byon W; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Weinzimmer D; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Tomasi G; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Nabulsi N; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Grimwood S; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Badura LL; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Carson RE; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • McCarthy TJ; Pfizer Inc., Groton, CT and Cambridge, MA, USA.
  • Huang Y; PET Center, Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Neuroimage ; 99: 69-79, 2014 Oct 01.
Article en En | MEDLINE | ID: mdl-24844744
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirrolidinas / Sulfonamidas / Compuestos de Bifenilo / Receptores Opioides kappa Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2014 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piperazinas / Pirrolidinas / Sulfonamidas / Compuestos de Bifenilo / Receptores Opioides kappa Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Año: 2014 Tipo del documento: Article