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Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.
Dandapani, Sivaraman; Germain, Andrew R; Jewett, Ivan; le Quement, Sebastian; Marie, Jean-Charles; Muncipinto, Giovanni; Duvall, Jeremy R; Carmody, Leigh C; Perez, Jose R; Engel, Juan C; Gut, Jiri; Kellar, Danielle; Siqueira-Neto, Jair Lage; McKerrow, James H; Kaiser, Marcel; Rodriguez, Ana; Palmer, Michelle A; Foley, Michael; Schreiber, Stuart L; Munoz, Benito.
  • Dandapani S; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Germain AR; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Jewett I; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • le Quement S; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Marie JC; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Muncipinto G; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Duvall JR; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Carmody LC; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Perez JR; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Engel JC; Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.
  • Gut J; Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.
  • Kellar D; Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.
  • Siqueira-Neto JL; Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.
  • McKerrow JH; Center for Discovery and Innovation in Parasitic Diseases, University of California San Francisco , 1700 Fourth Street, San Francisco, California 94158, United States.
  • Kaiser M; Swiss Tropical and Public Health Institute , Socinstr. 57, Basel, Switzerland ; University of Basel , Petersplatz 1, 4003 Basel, Switzerland.
  • Rodriguez A; Department of Microbiology, New York University School of Medicine , 550 First Avenue, New York, New York 10016, United States.
  • Palmer MA; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Foley M; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
  • Schreiber SL; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States ; Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Harvard University , Cambridge, Massachusetts 02138,
  • Munoz B; Center for the Science of Therapeutics, Therapeutics Platform, Broad Institute of MIT and Harvard , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.
ACS Med Chem Lett ; 5(2): 149-53, 2014 Feb 13.
Article en En | MEDLINE | ID: mdl-24900788
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2014 Tipo del documento: Article