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CNS amyloid-ß, soluble APP-α and -ß kinetics during BACE inhibition.
Dobrowolska, Justyna A; Michener, Maria S; Wu, Guoxin; Patterson, Bruce W; Chott, Robert; Ovod, Vitaliy; Pyatkivskyy, Yuriy; Wildsmith, Kristin R; Kasten, Tom; Mathers, Parker; Dancho, Mandy; Lennox, Christina; Smith, Brad E; Gilberto, David; McLoughlin, Debra; Holder, Daniel J; Stamford, Andrew W; Yarasheski, Kevin E; Kennedy, Matthew E; Savage, Mary J; Bateman, Randall J.
  • Dobrowolska JA; Departments of Neurology and.
  • Michener MS; Safety and Laboratory Animal Resources.
  • Wu G; Molecular Biomarkers.
  • Patterson BW; Medicine, Washington University School of Medicine, St. Louis, Missouri 63110 and.
  • Chott R; Medicine, Washington University School of Medicine, St. Louis, Missouri 63110 and.
  • Ovod V; Departments of Neurology and.
  • Pyatkivskyy Y; Departments of Neurology and.
  • Wildsmith KR; Departments of Neurology and.
  • Kasten T; Departments of Neurology and.
  • Mathers P; Safety and Laboratory Animal Resources.
  • Dancho M; Safety and Laboratory Animal Resources.
  • Lennox C; Safety and Laboratory Animal Resources.
  • Smith BE; Safety and Laboratory Animal Resources.
  • Gilberto D; Safety and Laboratory Animal Resources.
  • McLoughlin D; Preclinical Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486 and Kenilworth, New Jersey 07033.
  • Holder DJ; Early Development Statistics, and.
  • Stamford AW; Medicinal Chemistry.
  • Yarasheski KE; Medicine, Washington University School of Medicine, St. Louis, Missouri 63110 and.
  • Kennedy ME; Neuroscience.
  • Savage MJ; Molecular Biomarkers.
  • Bateman RJ; Departments of Neurology and batemanr@wustl.edu.
J Neurosci ; 34(24): 8336-46, 2014 Jun 11.
Article en En | MEDLINE | ID: mdl-24920637
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistema Nervioso Central / Péptidos beta-Amiloides / Precursor de Proteína beta-Amiloide / Secretasas de la Proteína Precursora del Amiloide Tipo de estudio: Clinical_trials / Guideline Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistema Nervioso Central / Péptidos beta-Amiloides / Precursor de Proteína beta-Amiloide / Secretasas de la Proteína Precursora del Amiloide Tipo de estudio: Clinical_trials / Guideline Límite: Animals / Humans Idioma: En Año: 2014 Tipo del documento: Article