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Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis.
Kass, Itamar; Hoke, David E; Costa, Mauricio G S; Reboul, Cyril F; Porebski, Benjamin T; Cowieson, Nathan P; Leh, Hervé; Pennacchietti, Eugenia; McCoey, Julia; Kleifeld, Oded; Borri Voltattorni, Carla; Langley, David; Roome, Brendan; Mackay, Ian R; Christ, Daniel; Perahia, David; Buckle, Malcolm; Paiardini, Alessandro; De Biase, Daniela; Buckle, Ashley M.
  • Kass I; Department of Biochemistry and Molecular Biology,Victorian Life Sciences Computation Initiative Life Sciences Computation Centre, and.
  • Hoke DE; Department of Biochemistry and Molecular Biology.
  • Costa MG; Programa de Computação Científica, Fundação Oswaldo Cruz, 21949900 Rio de Janeiro, Brazil;
  • Reboul CF; Department of Biochemistry and Molecular Biology,Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Clayton, VIC 3800, Australia;
  • Porebski BT; Department of Biochemistry and Molecular Biology.
  • Cowieson NP; Australian Synchrotron, VIC 3168, Australia;
  • Leh H; Laboratoire de Biologie et de Pharmacologie Appliquée, Ecole Normale Supérieure de Cachan, Centre National de la Recherche Scientifique, 61, F-94235 Cachan, France;
  • Pennacchietti E; Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Sapienza Università di Roma, 04100 Latina, Italy;
  • McCoey J; Department of Biochemistry and Molecular Biology.
  • Kleifeld O; Department of Biochemistry and Molecular Biology.
  • Borri Voltattorni C; Dipartimento di Scienze della Vita e della Riproduzione, Sezione di Chimica Biologica, Facoltà di Medicina e Chirurgia, Università degli Studi di Verona, 37134 Verona, Italy;
  • Langley D; Garvan Institute of Medical Research, Darlinghurst/Sydney, NSW 2010, Australia; and.
  • Roome B; Garvan Institute of Medical Research, Darlinghurst/Sydney, NSW 2010, Australia; and.
  • Mackay IR; Department of Biochemistry and Molecular Biology.
  • Christ D; Garvan Institute of Medical Research, Darlinghurst/Sydney, NSW 2010, Australia; and.
  • Perahia D; Laboratoire de Biologie et de Pharmacologie Appliquée, Ecole Normale Supérieure de Cachan, Centre National de la Recherche Scientifique, 61, F-94235 Cachan, France;
  • Buckle M; Laboratoire de Biologie et de Pharmacologie Appliquée, Ecole Normale Supérieure de Cachan, Centre National de la Recherche Scientifique, 61, F-94235 Cachan, France;
  • Paiardini A; Dipartimento di Scienze Biochimiche "A. Rossi Fanelli," Sapienza Università di Roma, 00185 Rome, Italy.
  • De Biase D; Istituto Pasteur-Fondazione Cenci Bolognetti, Dipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Sapienza Università di Roma, 04100 Latina, Italy;
  • Buckle AM; Department of Biochemistry and Molecular Biology, ashley.buckle@monash.edu.
Proc Natl Acad Sci U S A ; 111(25): E2524-9, 2014 Jun 24.
Article en En | MEDLINE | ID: mdl-24927554
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autoinmunidad / Neurotransmisores / Simulación de Dinámica Molecular / Ácido gamma-Aminobutírico / Glutamato Descarboxilasa / Homeostasis Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Autoinmunidad / Neurotransmisores / Simulación de Dinámica Molecular / Ácido gamma-Aminobutírico / Glutamato Descarboxilasa / Homeostasis Límite: Humans Idioma: En Año: 2014 Tipo del documento: Article